Isotopic Scintigraphy in Intrathecal Drug Delivery Failure: A Single‐Institution Case Series
نویسندگان
چکیده
منابع مشابه
Gamma scintigraphy in the evaluation of drug delivery systems [Persian]
Gamma-scintigraphy is applied extensively in the development and evaluation of pharmaceutical delivery systems, particularly for monitoring formulations in the gastrointestinal and respiratory tracts. The radiolabelling is generally achieved by the incorporation of an appropriate radionuclide such as technetium-99m or indium-111 into the formulation or by addition of a non-radioactive iso...
متن کاملNear-fatal drug toxicities in newborn babies: A Case Series
Background: Neonates are highly vulnerable to drug toxicities because of their age-related limitations in drug metabolisms and renal excretion. Lack of the knowledge and/or education for medical professionals about the right dose administration and the lack of neonate-specific formulations are the additional dilemmas. Cases Presentation: Here, we reported six neonates presented with severe ...
متن کاملIsotopic scintigraphy combined with computed tomography: a useful method for investigating inefficiency of intrathecal baclofen.
BACKGROUND Intrathecal baclofen infusion is an established method for the treatment of generalized and disabling spasticity. The most frequent technical problems are due to catheter /pump disconnections, but diagnosis of dysfunction may be difficult. CASE REPORT We report here the case of a 53-year-old woman with spastic paraplegia treated with intrathecal baclofen. Spasticity remained uncont...
متن کاملCurrent perspectives on intrathecal drug delivery
Advances in intrathecal analgesia and intrathecal drug delivery systems have allowed for a range of medications to be used in the control of pain and spasticity. This technique allows for reduced medication doses that can decrease the side effects typically associated with oral or parenteral drug delivery. Recent expert panel consensus guidelines have provided care paths in the treatment of noc...
متن کاملFluid Mechanics of Intrathecal Drug Delivery
The aim of this principally experimental study is to understand from fluid mechanic principles why an insignificant anesthetic dose administered as a short bolus into the cerebrospinal fluid inside the subarachnoid space provides greater pain relief than a larger dose continuously injected over a longer period. The subarachnoid space is modeled as an annular gap of constant or slowly varying cr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuromodulation: Technology at the Neural Interface
سال: 2020
ISSN: 1094-7159,1525-1403
DOI: 10.1111/ner.13275